Notes about the effects of Coffee and Caffeine


Preparing for caffeine ingestion
Preparing for caffeine ingestion


When active and awake, brain cells produce adenosine and export it to adenosine receptors found in the surface of the cells. This contributes to a slow-down in the transmission of neural signals and the adenosine build-up causes the brain to work ever slower, inducing the state of tiredness, signaling the body it needs a break.

The molecular structure of caffeine is very similar to that of adenosine, being able to bind itself to the adenosine receptors as well. However, caffeine does not contribute to a slow-down of the brain-cell activity. In other words, caffeine does not stimulate, as it is often thought, but it obstructs that tiredness takes place, indirectly causing that the brain’s own stimulants – like adrenalin and endorphin – increase their activity.

It is thus not a drug addiction what coffee drinking could cause, but, if used too often and improperly, a vicious cycle will take place. When the brain cells signal tiredness because an earlier pause did not take place, we tend to ingest even more coffee or caffeine.

It is more accurate to say that caffeine misuse may lead to dependence. No wonder studies repeatedly indicate three to four cups of coffee to be a caffeine amount that the body could healthfully deal with.


After caffeine ingestion, undrinkable rests



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